大剂量灯盏细辛注射液硬膜外腔灌注治疗椎动脉型颈椎病的临床研究  

Clinical Research of Perfusion in Epedural Space with Large Dose of Deng zhanxixin in Cervical Spondylosis of Arteria Vertebralis

作　　者：伊智雄[1] 籍文强[1] 牛杰杰[1] 徐琳[1] 张立庄[1] 王建兵[1] 朱俊清[1] 

机构地区：[1]河北医科大学第一医院中西医结合脊柱病科,石家庄050031

出　　处：《中国现代医生》2007年第10S期18-20,22,共4页China Modern Doctor

基　　金：河北省科技厅科技攻关计划项目(052761630)

摘　　要：目的观察大剂量灯盏细辛注射液硬膜外腔灌注治疗椎动脉型颈椎病的临床效果。方法以2005年1月～2006年12月椎动脉型颈椎病120例为研究对象,观察和记录大剂量灯盏细辛注射液硬膜外腔灌注治疗前后临床主要自觉症状的模拟评分,评定治疗效果。结果大剂量灯盏细辛注射液硬膜外腔灌注结束时即刻开始观察,治疗后所有临床主要自觉症状的模拟评分较治疗前皆显著降低(P<0.01);与治疗前比较,各观察阶段的疗效皆有显著性差异。结论大剂量灯盏细辛注射液硬膜外腔灌注治疗椎动脉型颈椎病有令人满意的的疗效。Objective To observe the effect of perfusion in epidural space with a large volume of Dengzhanxixin injection in treatment of cervical spondylosis of arteria vertebralis. Methods 120 patients with cervical spondylosis of arteria vertebralis were involved in our study from Jan 2005 to Dec 2006. All patients received perfusion therapy in epidural space with large dose of Dengzhanxixin. The observation began immediately after treatment and the changes of cardinal symptoms were recorded and evaluated by analogue scoring before and after treatment. Results The scores of each symptom decreased markedly after treatment. Compared with that before treatment, there was significant difference in statistics（P 〈 0.01） Conclusion Treatment of cervical spondylosis by perfusion in epidaral space with a large volume of Dengzhan Xixin injection has remarkable and effective therapeutic efficacy.

关 键 词：颈椎病 灯盏细辛注射液 大剂量 硬膜外腔灌注 疗效 

分 类 号：R681.55[医药卫生—骨科学]