耐力训练和急性力竭运动对大鼠组织金属硫蛋白含量的不同影响  

THE EFFECT OF ENDURANCE TRAINING AND EXHAUSTIVE EXERCISE ON METALLOTHIONEIN IN RATS

作　　者：李昭波[1] 高云秋[1] 李淑敏[1] 陈魁 葛淑君[1] 庞永正[1] 唐朝枢[1] 

机构地区：[1]北京医科大学运动医学研究所

出　　处：《中国应用生理学杂志》1997年第1期16-17,共2页Chinese Journal of Applied Physiology

基　　金：国家自然科学基金

摘　　要：为探讨金属硫蛋白（ＭＴ）在运动提高机体自我保护能力方面的作用，本实验观察了游泳运动对大鼠心、肝、肺、脑、血管、血浆和骨骼肌等７种组织金属硫蛋白含量的影响。结果表明耐力训练组大鼠心、肝、肺和骨骼肌组织金属硫蛋白含量较正常对照组明显降低１３－３４％（Ｐ＜０．０５）；急性力竭运动组大鼠心、肝、脑、肺和骨骼肌组织其含量较正常对照组则明显升高２１－７５％（Ｐ＜０．０５）；但两组大鼠血管和血浆ＭＴ含量变化与对照组大鼠相比无统计学意义（Ｐ＜０．０５）。推测各组织金属硫蛋白在不同运动形式下的不同变化可能在运动提高机体自我保护能力方面具有积极意义。To understand physiological role of metallothionein (MT) during exercise, MT levels in liver, brain,heart,lung,blood vessel,skeletal muscle and serum were observed in rats.The results showed that the levels of MT were decreased by 13-34% in lung,liver, heart and skeletal muscle of rats trained by swimming for 10 weeks and were increased by 21%-75% in skeletal muscle,heart,brain, lung and liver of rats after exhaustive swimming respectively,compared with normal control rats.( P <0.05 and P <0.01). But the levels of MT in blood vessel and serum were not changed in two groups of rats by swimming for 10 weeks and acute exhaustive swimming ( P >0.05).It is suggested that the different changes of MT levels under physical training and acute exhaustive exercise may be of importance in protection against oxygen free radicals.

关 键 词：运动生理学 金属硫蛋白 耐力训练 运动 

分 类 号：G804.21[文化科学—运动人体科学]