膝关节骨关节炎的严重程度与下肢脂肪、肌肉及骨矿比的关系  

Relationship between Progression of Knee Osteoarthritis and Ratio of Fat,Lean or Bone Mineral Content

作　　者：于志锋[1] 安丙辰[1] 胡琪良[1] 戴尅戎[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院骨科,上海市200011

出　　处：《中国康复理论与实践》2007年第9期891-892,共2页Chinese Journal of Rehabilitation Theory and Practice

基　　金：上海交通大学医学院附属第九人民医院基金

摘　　要：目的研究膝关节骨关节炎的严重程度与下肢局部肌肉、脂肪及骨矿含量的关系。方法原发性膝关节骨关节炎女性患者31例,36个膝关节,根据是否存在关节间隙狭窄分为关节间隙狭窄和不狭窄组,两组患者均登记基本信息,计算体重指数,拍摄负重位膝关节正位X线片,利用双能X线骨密度检测仪检测患肢的脂肪、肌肉及骨矿含量。结果两组患者在患肢侧别和年龄分布上没有显著性差异(P>0.05),骨关节炎膝关节间隙狭窄组的体重指数和脂肪含量大于关节间隙不狭窄组(P<0.05),下肢的肌肉含量低于关节间隙不狭窄组(P<0.05),骨矿含量无显著性差异。结论体重指数和局部脂肪含量的升高以及肌肉含量的减少可能是导致女性膝关节骨关节炎患者病情加重的重要因素。　Objective To study the relationship between knee osteoarthritis progression and the ration of fat,lean,or bone mineral content（BMC）.Methods 36 joints of knee with osteoarthritis in 31 women were divided into two groups according to the knee joint space,joint space narrowing group and non-narrowing group.The body mass index（BMI）was calculated.The X-ray（weight bearing）of knee joint was taken.The fat,lean,BMC and mass of leg were detected with the dual energy X-ray absorptiometry（DXA）.Results There was no distinct difference between sides and age distribution for the tested groups（P〉0.05）.The BMI and fat/mass ratio of leg in the joint space narrowing group were obviously higher than that of the non-narrowing group（P〈0.05）,while the lean/mass ratio of leg in the joint space narrowing group was distinctly lower than that of the non-narrowing group（P〈0.05）.Conclusion The deterioration of the female knee osteoarthritis can be mainly attributed to the increase of the BMI and fat/mass ratio as well as the decrease of the lean/mass ratio of leg.

关 键 词：膝关节 骨关节炎 脂肪 肌肉 骨矿 

分 类 号：R684.3[医药卫生—骨科学]