经皮球囊肺动脉瓣成形术16例临床分析  

Clinical Observation on 16 Patients Underwent Percutaneous Balloon Pulmonary Valvuloplasty

作　　者：闫培全 任末翎 朱慧 王丽莉 

机构地区：[1]山东省威海卫人民医院心内科,264200

出　　处：《实用全科医学》2007年第10期864-865,共2页Applied Journal Of General Practice

摘　　要：的观察经皮球囊肺动脉瓣成形术(Percutaneous balloon pulmonary valvuloplasty,PBPV)治疗单纯性先天性肺动脉瓣狭窄(Isolated congenital pulmonary valve stenosis,ICPS)的临床效果。方法16例行PBPV治疗患者于术前、术后测量右室收缩压(right ventricle systolic pressure,RVSP)及肺动脉与右心室跨瓣压差(pressure gradient,PG),并观察术前、术后3d、术后1年的心电图、心脏彩超结果。结果术后即刻RVSP由(102.63±12.58)mm Hg降至(61.38±42.10)mm Hg(P<0.01);PG由(80.29±21.20)mm Hg降至(27.54±12.71)mm Hg(P<0.01)。随诊1年,二者进一步下降(P<0.01)。术前16例心电图提示右室高电压、T波异常者中,术后3d3例(20.00%)右室肥厚消失,12例(75.00%)T波恢复倒置,术后1年内心电图全部恢复正常。结论PBPV安全有效,是治疗肺动脉瓣狭窄的首选方法。Objective To evaluate the recent and long-term effectiveness of Percutaneous Balloon Pulmonary Valvuloplasty （PBPV） for isolated congenital pulmonary valve stenosis （ICPS）. Methods The right ventricle systolic pressure （RVSP） and pressure gradient（PG） across the pulmonary valve were observed before and after PBPV in 16 patients with ICPS,electrocardiogram and echocardiogram were taken in the follow-up of one year. Results The RVSP decreased from（ 102.63 ± 12.58） mm Hg to（61.38 ± 42.10） mm Hg（ P 〈 0.01 ） and PG decreased from （ 80.29 ± 21.20） mm Hg to（ 27.54± 12.71 ） mm Hg（ P 〈 0.01 ） immediately after PBPV and decreased significantly in 1 year. The right ventricular hypertrophy in 3 cases（20.00% ） and T wave inversion in 12 cases（75.00% ） recovered 3 days after PBPV,The abnormalities in electrocardiogram in all patients（ 16 cases） disappeared in 1 year. Conclusions PBPV is a safe and effective method and is the first choice for ICPS.

关 键 词：单纯性先天性肺动脉狭窄(ICPS) 经皮球囊肺动脉瓣成形术(PBPV) 

分 类 号：R654.27[医药卫生—外科学]