游泳对慢性应激抑郁症模型大鼠行为学及脑内神经递质的影响  

Effects of Swimming on Behavior and Monoamine Neurotransmitters in the Brain in Rat Model of Chronic Unpredictable Stress Depression

作　　者：杨银田[1] 崔冬雪[1] 季彦霞[2] 李继东[2] 郭立涛[2] 

机构地区：[1]河北师范大学体育学院,河北石家庄050016 [2]河北体育学院,河北石家庄050041

出　　处：《成都体育学院学报》2007年第5期96-99,共4页Journal of Chengdu Sport University

摘　　要：方法:60只雄性SD大鼠,随机分为对照组(C)、运动组(E)、模型组(M)、运动应激组(ES)和运动应激运动组(ESE)。实验共14周。实验结束后,利用荧光分光光度法检测检测应激及游泳锻炼对单胺类神经递质含量的影响,探讨游泳锻炼预防抑郁的机制。结果:游泳锻炼能够升高应激状态下动物脑内NE、DA、5-HT的含量(P<0.01)。结论:游泳锻炼调节下丘脑组织中的DA、NE和海马组织中5-HT的含量可能是预防抑郁症的机制。Methods ： In this experiment, 60 SD male rats are devided into 5 groups at random ： group C （ comparing group）, group E （exercise）, group M （model）, group ES （exercise stress）, and group ESE （exercise stress exercise）. This experiment lasts 14weeks. After finishing the experiment, through fluorospectrophotometry, the author detects stress＇and swimming＇s effect on quantity of monoamine neurotransmitter, and discusses the system to prevent depression by swimming. Result ： In stress situation, swimming can increase the quality of NE, DA, and 5 - HT in animal brain. Conclusion： The system to prevent depression could be to cooperate the quality of NE as well as DA in hypothalamus and the quality of 5 - HT in hippocampus.

关 键 词：单胺类神经递质 抑郁症 游泳锻炼 荧光分光光度法 

分 类 号：G861.1[文化科学—体育训练]