微针经皮给药技术  

Microneedles in Transdermal Drug Delivery System

作　　者：唐国春[1] 詹晓平[1] 陈思静[1] 毛振民[1] 

机构地区：[1]上海交通大学药学院,上海200240

出　　处：《药学进展》2007年第9期385-390,共6页Progress in Pharmaceutical Sciences

摘　　要：微针是介于皮下注射和透皮贴剂之间的一种给药方式,利用在皮肤角质层产生的微小孔道来显著增加药物的经皮吸收。综述微针经皮给药技术的研究进展,介绍制造微针的材料和方法、微针的给药方式及其在经皮给药系统中的应用。The development of microneedles in transdermal drug delivery system was reviewed, including the materials used, manufacturing method, administration and application. Microneedles administration, as one of drug delivery approaches between hypodermic needle and transdermal patch, can remarkably increase the permeability of drugs by forming minimal pores in stratum comeum. With the development of this technology, microneedles is becoming a promising approach to transdermal drug delivery and will create a big economic profit.

关 键 词：微针 经皮吸收 给药方式 

分 类 号：R94[医药卫生—药剂学] R452[医药卫生—药学]