儿童再发性腹痛与幽门螺杆菌粪便抗原检测阳性的关系  

The relationship between children with recurrent abdominal pain and the Helicobacter pylori stool antigen test

作　　者：王玉琼[1] 司徒勋[1] 谢志伟[1] 

机构地区：[1]广州市儿童医院儿内科,510120

出　　处：《广州医药》2007年第5期36-38,共3页Guangzhou Medical Journal

摘　　要：目的探讨儿童再发性腹痛(RAP)与幽门螺杆菌粪便抗原(HP-SA)检测阳性的关系。方法采用流动色谱技术快速检测粪便中的HP抗原,再对RAP组的68例阳性患儿进行13C尿素呼气试验(13C-UBT)检查。结果RAP组的300例儿童,HP-SA检测阳性者131例,检出率43.67%,高于正常对照组,P<0.05;RAP组的男女性别感染率均无显著性差异,P>0.05;学龄儿童HP-SA阳性率高于学龄前儿童,P<0.05;3岁以上儿童,随着年龄增长,HP-SA阳性率呈增高趋势。RAP组的68例HP-SA检测阳性患儿中13C-UBT阳性者58例,检出率85.29%。结论①儿童RAP中上消化道疾病占较高比率,HP感染可能是引起RAP的主要原因之一,儿童HP感染状况不容忽视;②HP-SA检测方法可作为初步筛选试验,根据其结果再进行13C-UBT检查判断HP感染。两种实验方法结合具有无创、准确、快速、相对经济的优点。Objective To discuss the relationship between children with recurrent abdominal pain and the Helicobacter pylori stool antigen test. Methods To detect HP-SA with flow chromatographic technique fast test. In the RAP, use ^13C-UBT to detect HP in 68 patients with HP-SA positive. Results In 300 children of the RAP, 131 patients are HP-SA positive, the positive rate is 43.67%, which is higher than that in the normal control. In the RAP, there is no obvious difference in sexual distinction, P 〉0.05. In the RAP, the positive rate in school children is higher than that in preschool children, P 〈0, 05, Above 3-year-children, the positive rate raises up with the age increasing. In the RAP, 68 children with HP-SA positive, ^13C-UBT positive patients are 58. The positive rate is 85.29%. Conclusion （1）The upper digestive tract deseases ocuppy high rate in children with RAP. HP infection maybe the one of main causes in RAP, HP infection in childen is important. （2）HP-SA test can become the initial shift test. To judge HP infection with ^13C-UBT after HP-SA test. These two methods use together are without trauma, accurate, fast and cheap.

关 键 词：幽门螺杆菌粪便抗原检测 儿童再发性腹痛 阳性者 13C尿素呼气试验 P〉0.05 上消化道疾病 HP抗原 HP感染 

分 类 号：R725.7[医药卫生—儿科]