加替沙星与左氧氟沙星治疗泌尿系统感染的疗效-成本分析  

Pharmacoeconomic analysis of gatifloxacin and levofloxacin in the treatment of urinary system infection

作　　者：梁燕芳[1] 孔令瑞[1] 邓雪媚[1] 

机构地区：[1]广东省肇庆市第一人民医院,526021

出　　处：《广州医药》2007年第5期62-64,共3页Guangzhou Medical Journal

摘　　要：目的比较加替沙星与左氧氟沙星治疗泌尿系统感染的成本-效果。方法采用药物经济学原理对两种治疗方案进行成本-效果分析。结果加替沙星与左氧氟沙星组治疗泌尿系统感染的有效率分别为93.75%、87.5%(P>0.05);不良反应发生率分别为6.3%、8.3%(P>0.05)。成本-效果比(C/E)分别为8.75、4.31。与左氧氟沙星组相比,加替沙星组每增加一个单位效果需多花费70.91元。结论左氧氟沙星治疗泌尿系统感染成本-效果比优于加替沙星。Objective To compare the cost-effectiveness of gatifioxacin and levofloxacin in the treatment of patients with infection in urinary system. Methods Principle of pharmacoeconomics was adopted to analyze cost-effectiveness of the two treatment schemes. Results The effective rates of gatifloxacin group and levofioxacin group in the treatment of urinary sys- tem infection were 93.75% and 87. 50% （ P 〉 0. 05 ） respectively; the incidence rate of adverse reactions were 6. 3% and 8.3% （ P 〉0. 05 ） ; the cost-effectiveness ratio （C/E） were 8.75 and 4. 31 respectively. The cost for every one unit increment of effectiveness for gatifloxacin group was 70. 91 yuan more than that of the levofioxacin group. Conclusion Cost-effectiveness ratio of levofioxacin is superior to that of gatifioxacin in the treatment of urinary system infection.

关 键 词：加替沙星 左氧氟沙星 泌尿系统感染 成本-效果分析 

分 类 号：R691.3[医药卫生—泌尿科学]