代谢综合征患者血超敏CRP水平与冠心病的关系  

Association of blood ultrasensitive C-reative protein level with coronary heart disease in the patients with metabolic syndrome.

作　　者：王奕晖 王家骥[2] 林倩敏 

机构地区：[1]广州市第六人民医院内分泌科,广东广州510655 [2]广州医学院公共卫生与全科医学学院,广东广州510182

出　　处：《四川医学》2007年第9期962-963,共2页Sichuan Medical Journal

基　　金：广东省科委社会发展攻关项目(2003C33709);广州市科技攻关立项资助项目;广州市卫生局立项资助项目

摘　　要：目的探讨超敏CRP(hsCRP)水平在不同代谢异常状态下与冠心病的关系。方法将243例不同程度代谢异常患者分为冠心病和非冠心病组,并测定血脂、血糖、hsCRP。结果代谢综合(MS)并冠心病患者hsCPR水平高于非冠心病者,并随着代谢异常因素的增多,hsCRP水平有所增加(P<0.05)。结论hsCRP可能是MS及其心血管病变(CHD)的危险因子,炎症可能参予了MS及冠心病的发生和发展。Objective To study the associations of the ultrasensitive C-reactive protein（hsCRP）with coronary heart diseasd （CHD）in different metabolic disorders.Methods 243 patients with different metabolic disorders was divided into two groups： CHD and without CHD, and measurements of the levels of serum lipids, blood glucose, hsCRP. Results A cross-sectional study of 243 patients was showed that the level of hsCRP in CHD was significantly higher than those without CHD, and with the major components of metabolic syndrome（MS） were increased. Conclusion The population with higher CRP level seems to be predisposed to MS and CHD,and play a role in the initiation and progression of MS and MS with CHD.

关 键 词：超敏CRP 代谢综合征 冠心病 

分 类 号：R589[医药卫生—内分泌] R541.4[医药卫生—内科学]