我院抗感染药物应用情况及病原菌药物敏感性分析  

Analysis of Using Anti-infective Agents and Tolerance of Isolated Strains in Clinic

作　　者：周霞[1] 易太友 郑红毅[1] 周建蓉 何文芳[1] 

机构地区：[1]四川省建筑医院,四川成都610081

出　　处：《中国药业》2007年第19期36-37,共2页China Pharmaceuticals

摘　　要：目的了解临床抗感染药物的使用及病原菌对抗感染药物的敏感性情况。方法收集2006年使用的抗感染药物的种类及数量、使用量占前10位的品种、革兰阳性菌(G+菌)和革兰阴性菌(G-菌)的药物敏感试验数据。结果头孢菌素类、青霉素类、喹诺酮类为临床用量最大的抗感染药物,分别占27.66%,22.60%,15.38%;G+菌对青霉素G、哌拉西林的耐药率分别为83.33%和48.72%,对阿米卡星的耐药率最低,为40.54%;G-菌对头孢哌酮、头孢曲松、头孢噻肟、头孢他啶、阿米卡星、左氧氟沙星的耐药率分别是22.51%,30.57%,30.94%,16.85%,9.40%,26.12%。结论临床应根据病原菌分布和药物敏感试验统计数据合理选用抗感染药物。Objective To know the status using anti-infective agents in clinic and the tolerance of isolated strains. Methods To collect the data of using anti- infective agents in clinic and tolerance of isolated strains. Results The amounts using cephalosporin, penicillin and quinolones, accounted for 27, 66%, 22.60%, 15, 38% respectively. Gram-positive bacteria kept higher tolerance, the tolerant rate was 83, 33% for benzylpencillin, 48.72% for piperaeilbn and 40, 54% for amlkacin respectively. Gram- negative bacteria kept lower tolerance, the tolerant rate was 22.51% for cefoperazon, 30. 57% for cefadroxil, 30, 94% for eefotaxime, 16. 85% for ceftazidime,9. 40% for amikacin and 26. 12% for levofloxacin respectively. Conclusion The anti- infective agents should be selected rationally according to the distribution of pathogenic bacteria and the statistical data of drug sensitivity test,

关 键 词：抗感染药物 病原菌 药物敏感试验 耐药性 

分 类 号：R978.1[医药卫生—药品] R915[医药卫生—药学]