腺苷脱氨酶和癌胚抗原联合检测胸积液对鉴别诊断作用的评价  

CULTURING CELLS IN VITRO FOR DETERMINING THE SENSIVITY AND THE CORRELATIVES WITH CLINICAL THERAPEUTIE EFFICIENCY OF CHEMOTHERAPEUTIC DRUG FOR ANLL

作　　者：何桥[1] 赵国耀[1] 邓晓华[1] 

机构地区：[1]广州市胸科医院

出　　处：《广东医学》1990年第6期17-19,16,共4页Guangdong Medical Journal

摘　　要：胸腔积液是胸肺科疾病及其他疾病的常见并发病之一,要判定积液的性质,单靠一般的生化常规、细胞学、细菌学是不够的。前两者对鉴别诊断的特异性不高,后两者其敏感性又低。近年来,国内外学者报道了用腺苷脱氨酶(ADA)活性测定对结核性胸水有很高的诊断价值;用癌胚抗原(CEA)The sensitivity of 22 ANLL to Chemotherapeutic drugs was determined by cutturing cells in vitro with drug, sensitive index (SI), mean sensitivey index (MSI) and combining sensitive index (CSI). It was found that SI can be used as a method for detecting drug sensitivity of Ara-C and Harringtonine but not so good for vincristine. Drug sensitivity test of MSI and CSI were better than SI. As acute leukemia is now currently treated with combined chemotherapy, so it is susgested that CSI is the most conveniont method for clinical suse.

关 键 词：胸腔积液 腺苷脱氨酶 癌胚抗原 

分 类 号：R446[医药卫生—诊断学]