急性心肌梗死再灌注后CK活性峰值出现时间与心功能关系的研究  

Study between the Time to Peak CK Activity and Heart Function in Patients with Reperfused Acute Myocardial Infarction

作　　者：陈还珍[1] 刘达瑾[1] 郭文玲[1] 李清[1] 李晓英[2] 李思进[1] 吕吉元[1] 

机构地区：[1]山西医科大学第一医院 [2]山西中医学院中西医结合医院

出　　处：《中西医结合心脑血管病杂志》2007年第10期942-943,共2页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

摘　　要：目的观察首次急性心肌梗死（AMI）且溶栓再通的病人肌酸激酶（CK）峰值出现时间与梗死范围和左室功能之间的关系。方法将66例首次AMI病人根据发病时间到CK峰值出现的时间分为两组,A组36例,CK峰值出现的时间〈12h;B组30例,CK峰值出现的时间〉12h。结果CK峰值出现时间较晚者的心功能在急性期及恢复期（5个月-7个月）均好于CK峰值出现时间较早者（P〈0.05）。结论CK峰值出现时间较晚反映了心肌得到较好的挽救。Objective To study the relationship between the times to peak create kinase activity and heart function in patients （pts） with reperfused acute myocardial infarction （AMI）.. Methods Based on the time to peak create kinase activity in pts with reperfused AMI, there were 66 pts in group A （successful reperfusion time 〈 12 hours） and 36 pts in group B （successful reperfusion time ≥12 hours）. The LVEF and EDV of left ventricle were calculated and analyzed by myocardial SPECT. Results Left ventricular ejection fraction was better in group B than that in group A（ P〈 0.05 ）, Conclusion The late peak CK had better myocardial salvage in pts with AMI who had successful reperfusion.

关 键 词：急性心肌梗死 CK峰值 出现时间 功能关系 CK活性 再灌注 AMI病人 左室功能 

分 类 号：R542.22[医药卫生—心血管疾病]