对硝基苯腙基取代丙二酸二乙酯的合成及晶体结构  

Synthesis and Crystal Structure of Diethyl Malonate Substituted by p-Nitro-Phenylhydrazonocarboxyl

作　　者：李延红[1] 张甜[1] 杨红兵[1] 王建平[1] 

机构地区：[1]洛阳师范学院化学化工学院

出　　处：《洛阳师范学院学报》2007年第5期75-77,共3页Journal of Luoyang Normal University

摘　　要：在冰盐浴条件下,对硝基苯胺重氮盐与丙二酸二乙酯反应,合成了标题化合物C_(13)H_(15)N_3O_7。经IR、~1HNMR、元素分析和X-射线单晶测定,确认了其结构。化合物属单斜晶系,C2/c空间群,晶胞参数:α=14.331(11)■,b=6.847(5)■,c=32.63(3)■,β=98.149(14)°,V=3169(4)■~3,Z=8,D_c=1.364Mg/m^3,μ=0.112 mm^(-1),F (000)=1360,R=0.0783,wR=0.2461。The title compound has been synthesized by the reaction of ice-salt bath using p-nitro-aniline diazonium salt and diethyl malonate. Its structure was confirmed by IR,1H NMR, elemental analysis and X-ray single-crystal diffraction. A crystal of the title compound is monoclinic with space group C2/c, α = 14.331 （ 11 ）A, b = 6.847（5）A, c = 32.63（3） A, β = 98. 149（14）°, V = 3169（4） A^3, Z = 8, Dc = 1.364 Mg/ m^3,μ = 0.112mm^-1, F（000） = 1360, R =0.0783, wR = 0.2461.

关 键 词：腙 丙二酸二乙酯 晶体结构 生物活性 

分 类 号：O626[理学—有机化学]