HPLC法测定复方中成药桔红止咳冲剂中柚皮甙的含量  

Quantitative Analysis of Naringin in Juhongzhike Chongji by HPLC

作　　者：何燕萍[1] 王雅玲[1] 

机构地区：[1]北京医科大学药学院应用药物研究所,100083

出　　处：《中草药》1997年第4期205-206,共2页Chinese Traditional and Herbal Drugs

摘　　要：用HPLC对桔红止咳冲剂中的柚皮甙作了定量分析、样品用甲醇提取，在VarianKYWGC187μm（220min×4．6mm）柱上，用甲醇-1％醋酸（33：67）作流动相，各成分能很好分离，以标准曲线法测定了不同批号的10批样品中柚皮甙的含量、结果表明本法简便、快速、重视性好，测定回收率达100．1％，RSD为1．18％。Quantitative analysis of naringin in 'Juhongzhike Chongji'was carried out by HPLC. Samples were extracted with methanol. An ODS column of Varian KYWG C_(18) 7 μm (220×4. 6 mm ) and mobile phase methanol-1 % acetic acid (33: 67)were etnployed. Calibration curve method was used to determined the contents of naringin in ten samples.Results showed that the method is simple,quick and reproducible. The recovery was 100. 1% and RSD 1. 18%.

关 键 词：HPLC 桔红止咳冲剂 柚皮甙 中成药 药物含量 

分 类 号：R284.1[医药卫生—中药学] R286.0[医药卫生—中医学]