神昌滴丸对中风病人ETCGRP的影响  

Clinical Effects of Shenchang Diwan on Treating Stroke and Affecting on ET CGRP

作　　者：方永奇[1] 李艳慧[1] 

机构地区：[1]广州中医药大学第一附属医院实验中心,广东广州510405

出　　处：《中华中医药学刊》2007年第10期1990-1991,共2页Chinese Archives of Traditional Chinese Medicine

基　　金：广东省科技厅攻关课题(2003C34403)

摘　　要：目的:观察神昌滴丸治疗中风病的临床疗效及对内皮素(ET)、降钙素基因相关肽(CGRP)的影响。方法:53例中风病人随机分为神昌滴丸治疗组31例,醒脑静对照组22例。观察病人的症状、体征、毒副作用,并测定血液中ET、CGRP的含量。结果:神昌滴丸明显改善中风症状和体征;治疗前后神识、语言、面瘫、上肢瘫、指瘫、下肢瘫、趾瘫都有显著改善,其中面瘫、指瘫、趾瘫改善程度优于对照组;显效率达38.71%、总有效率达77.42%,高于对照组(18.18%、63.64%);神昌滴丸有降低ET、升高CGRP的作用;临床使用未见明显毒副作用。结论:神昌滴丸对中风病有良好的治疗作用,能舒张脑血管,改善脑供血。Objective： To observe the clinical effects of Shenchang diwan on treating stroke and affecting on ET, CGRP. Methods： 53 cases were divided to two groups： Shenchang diwan group （31） and Xingnoujing group（22）. The symptoms, signs, side - effects, ET and CGRP were observed. Results ： Shenchang diwan alleviated symptoms and signs of stroke patients. Consciousness, tongue, paralysis in face, upper limbs, finger, lower limbs and toe were improved after treatment, in which paralysis in face, finger and toe in Shenchang diwan group were get more better than that in control group. Obvious efficiency rat（38.71% ）, total efficiency rat （77.42%） in Shenchang diwan group were better than that in control group（ 18.18% ,63.64% ）. Shenchang diwan could decrease ET but increase CGRP in patient＇ s blood. No marked side - effect were observed after treatment. Conclusion ： Shenchang diwan is effect to stroke and improving blood supply of brain.

关 键 词：神昌滴丸 中风病 ET CGRP 

分 类 号：R255.2[医药卫生—中医内科学]