益气健脾化痰祛瘀中药对扩张型心肌病患者白细胞介素-2受体的影响  

Effects of Chinese Medicine Qiangxin Granule on SIL-2R to Patients With Dilated Cardiomyopathy

作　　者：邓斌[1] 陈芸[1] 何绪屏[1] 罗陆一[1] 李伟雄[1] 吕琪[1] 张尚斌[1] 肖少寒 

机构地区：[1]深圳市中医院,广东深圳518033 [2]深圳市罗湖区妇幼保健院,广东深圳518000

出　　处：《中华中医药学刊》2007年第10期2064-2065,共2页Chinese Archives of Traditional Chinese Medicine

基　　金：广东省中医药管理局课题(1040161A);深圳市科技计划项目(JH200505260256A)

摘　　要：目的:观察扩张型心肌病患者白细胞介素-2受体(SIL-2R)的水平以及益气健脾化痰祛瘀中药强心冲剂对其水平的影响。方法:将68例扩张型心肌病患者随机分为对照组和治疗组,对照组给予西医治疗,治疗组给予口服益气健脾化痰祛瘀中药强心冲剂。采用双抗体夹心ABC-ELISA法检测两组治疗前后白细胞介素-2受体含量并与健康成年人34例进行对比。结果:扩张型心肌病患者白细胞介素-2受体含量显著高于健康成人组,经中药治疗后其白细胞介素-2含量明显下降,而西药对照组治疗前后无明显差异。结论:扩张型心肌病的病变可能与白细胞介素-2相关,益气健脾化痰祛瘀中药可以调节扩张型心肌病患者白细胞介素-2受体水平,从而调节免疫反应。Objective ： The objective of this project （ research ） is to investigate the effect of Qiangxin granule of SIL - 2R on patients with Dilated Cardiomyopathy. Methods： In this study, 68 eases of patients with Dilated Cardiomyopathy were randomly divided into western medicine control group and Chinese medicine treated group. The treatment period is one month. The SIL- 2R levels were measured before and after the treatment with（using） radioimmune method. Results： The results indicate （show） that the SIL -2R levels of Dilated Cardiomyopathy patients were higher than those of healthy person＇s group apparently. The SIL -2R levels of the Chinese medicine group were reduced obviously. The SIL-2R levels of western medicine group were not changed significantly （apparently）. Conclusion： Our conclusions from this study are that the SIL -2R level of Dilated Cardiomyopathy patient are higher than that of healthy person. The traditional Chinese medicine can adjust the SIL -2R level of Dilated Cardiomyopathy.

关 键 词：扩张型心肌病 白细胞介素-2受体 强心冲剂 益气健脾化痰祛瘀 

分 类 号：R259.422[医药卫生—中西医结合]