自然留样法考察舒必利片的稳定性  

Stability of Sulpiride Tablet Obtained in Room Temperature

作　　者：高剑峰[1] 任敏[1] 柳玉勇[1] 

机构地区：[1]山东省安康医院,山东济宁272051

出　　处：《中国药业》2007年第20期32-33,共2页China Pharmaceuticals

摘　　要：目的考察舒必利片的稳定性。方法采用紫外分光光度法测定含量,对有关物质检查、性状、脆碎度、溶出度及微生物限度的考察均采用中国药典规定的方法。结果试制的3批样品各项指标在室温条件下,24个月内均无明显变化。结论本品应密封包装,注意防止吸潮,24个月内稳定性良好。Objective To observe the stability of Sulpiride Tablet. Methods The contents were determined with ultraviodet spectrophotometry, and the degradation products, properties, hardness and dissolution were inspected with the method in Chinese Pharmacopoeia. Results Three batches of samples were produced in the experiments and obtained in room temperature, the tablets had no change in 24 months. Conclusion If the tablet is sealed and kept from wet, they are steady in 24 months.

关 键 词：舒必利片 稳定性 紫外分光光度法 薄层色谱法 

分 类 号：R927.11[医药卫生—药学] R971.41