N'-(4,6-二取代嘧啶-2-基)氧化烟酰硫脲的合成与生物活性测定  

Synthesis and Biological Activity of Oxidized Nicotinicacyl Thiourea Derivatives

作　　者：李景智[1] 薛思佳[1] 郭彦玲[1] 

机构地区：[1]上海师范大学生命与环境科学学院,上海200234

出　　处：《有机化学》2007年第10期1278-1281,共4页Chinese Journal of Organic Chemistry

摘　　要：合成并表征了9种未见文献报道的N'-(4,6-二取代嘧啶-2-基)氧化烟酰硫脲衍生物3,结构经IR,1HNMR,元素分析得到确证.初步的生物活性测试表明化合物3a具有较好的除草活性,化合物3b具有一定的杀虫活性.Nine new N′-（4,6-disubstituted pyrimidin-2-yl）-N-oxidized nicotinicacyl thiourea derivatives 3 have been synthesized and characterized. The structures of 3 were conformed by IR, ^1H NMR spectra and elemental analysis. The preliminary biological tests showed that compound 3a has good herbicidal activities and compound 3b has good insecticidal activities.

关 键 词：N′-(4 6-二取代嘧啶-2-基)-N-氧化烟酰硫脲 2-氨基-4 6-二取代嘧啶 合成 生物活性 

分 类 号：TQ450[化学工程—农药化工]