太原地区戊型肝炎流行特征及其危险因素  

Epidemiological Characteristics and Risk Factors of Hepatitis E in Taiyuan

作　　者：张志敏[1,2] 王俊升[1,2] 姜丽丽[1,2] 贺启英[1,2] 王晶晶[1,2] 

机构地区：[1]山西医科大学公共卫生学院流行病教研室 [2]太原市传染病医院

出　　处：《中华预防医学杂志》1997年第3期144-146,共3页Chinese Journal of Preventive Medicine

摘　　要：为了解本地区戊型肝炎（ＨＥ）流行特征及危险因素，于１９９４年３～１２月对３８５例急性散发性病毒性肝炎进行血清学分型。结果：甲型肝炎１９１例（４９．６１％），乙型肝炎１０４例（２７．０１％），丙型肝炎２０例（５．１９％），ＨＥ３４例（８．８０％），未能分型２２例（５．７２％）。ＨＥ男∶女为６．５∶１，发病平均年龄３８．５岁；临床特点：起病急，病程短，预后好；３例ＨＥ孕妇中，１例发生死胎。将１９９３～１９９４年确诊的７０例ＨＥ病人作病例组，按性别年龄配比选７０例非肝炎病人作对照，进行配比病例对照研究，经单因素和多因素条件ｌｏｇｉｓｔｉｃ回归分析表明：在外用餐史（ＯＲ２．０１，９５％ＣＬ１．２８～３．１５），肝炎接触史（ＯＲ６．０４，９５％ＣＬ１．２４～２９．２９），不洁饮食史（ＯＲ２．１６，９５％ＣＬ２．０５～２．２６），３个因素为本病的主要危险因素。We investigated epidemiologically the risk factors of hepatitis E in Taiyuan. Of 385 patients with acute viral hepatitis collected, 191(49.61%) were serologically identified to have hepatitis A, 104(27.01%) HB, 34 (8.80%) HE, 20(5.19%) HC and 22(5.72%) unidentified types. The male to female ratio of HE as 6.5∶1. The median age of occurrence in the patients with HE was 38.5 years. One of three pregnant women with HE developed premature labor with fetal wastage. Case contorl study was conducted in 70 patients with HE and 70 controls. The controls were selected from other subjects with no histories of hepatitis and matched by age and sex. The data were dealed with single factor analysis and conditional logistic regression analysis. The results showed that eating meals in resturants ( OR 2.01, 95% CL 1.28～3.15), contacting with hepatitis case ( OR 6.04, 95% CL 1.24～ 29.29), ingesting dirty drink ( OR 2.16, 95% CL 2.05～2.26) are the major risk factors for HE.

关 键 词：戊型肝炎 危险因素 血清分型 流行病学 

分 类 号：R512.630.1[医药卫生—内科学]