紫外分光光度法测定心脏停搏液中盐酸普鲁卡因的含量  

Determination of procaine hydrochloride in cardiac standstill solution by ultraviolet spectrophotometry

作　　者：邓渝林[1] 唐蕾[1] 江春霞[1] 李欢欢[1] 张纯[1] 

机构地区：[1]第二军医大学长征医院药学部,上海200003

出　　处：《药学实践杂志》2007年第5期328-330,共3页Journal of Pharmaceutical Practice

摘　　要：目的：建立心脏停搏液中盐酸普鲁卡因的含量测定方法。方法：采用紫外分光光度法，检测波长为290nm。结果：盐酸普鲁卡因在0．5～8μg／mL范围内与吸收度呈线性关系（r=0．9999），平均回收率为98．59％，RSD为0．033％，n=9。结论：该方法操作简便、快速，结果准确，专属性强，适用于心脏停搏液中普鲁卡因的含量测定。Objective： To establish a method for the determination of the content of procaine hydrochloride in cradiac standstill solution. Method ： Ultraviolet spectrophotometric method was used to directly determine the content of procaine hydrochloride. The wavelength of detection was 290nm. Results ：The liner range was 0.5 - 8μg/mL（ r =0. 999 9） . The relative recovery of the method was 98.59% with RSD of 0. 033%. Conclusions： This method is simple ,rapid, accurate and can be used to determine the content of procaine hydrochloride in the preparation .

关 键 词：紫外分光光度法 盐酸普鲁卡因 心脏停搏液 含量测定 

分 类 号：R917[医药卫生—药物分析学]