HPLC法测定乳癖消片中芍药苷含量  

Determination of paecniflorin in Rupixiao tablets by HPLC

作　　者：姜云云[1] 潘亚菊[1] 范国荣[1] 

机构地区：[1]第二军医大学药学院,上海200433

出　　处：《药学实践杂志》2007年第5期330-331,333,共3页Journal of Pharmaceutical Practice

摘　　要：目的-建立HPLC法测定乳癖消片中芍药苷含量的方法。方法：采用DiamonsilC18色谱柱，乙腈-水（20：80）为流动相，流速1．0mL／min，检测波长为230nm。结果：芍药苷线性范围为4．0～16．0μg／mL，平均回收率为99．75％，RSD为1．07％。结论：该方法简便、可靠、准确，可用于该制剂的质量控制。Objective ： To establish a method of HPLC for determination of paecniflorin in Rupixiao tablets. Methods： A Diamonsil C18 column was used. The mobile phase was acetonitrile-water （20： 80）. The flow rate was 1.0 mL/min. The detection wavelength was set as 230 nm. Results：The linear range of paecniflorin was 4.0 - 16.0μg/mL, and the average recovery rate was 99.75%, RSD was 1.07%. Conclusion：The method is simple, reliable, and accurate and can be applied to the quality control of preparation.

关 键 词：乳癖消片 芍药苷 HPLC 

分 类 号：R917[医药卫生—药物分析学]