哮喘大鼠气管微循环中白细胞粘附的活体观察  

In Vivo Observation of Leukocyte Adherence in Asthmatic Rats

作　　者：苗会[1] 胡清华[1] 薛全福[2] 新见英幸 庄逢源[1] 

机构地区：[1]中日友好临床医学研究所血液流变研究室 [2]中国医学科学院中国协和医科大学基础医学院病理生理研究室 [3]日本国立循环器病中心研究所微循环科学部

出　　处：《微循环学杂志》1997年第2期4-5,共2页Chinese Journal of Microcirculation

摘　　要：哮喘大鼠气管微循环中白细胞粘附的活体观察／苗会，胡清华，薛全福，等／北京中日友好临床医学研究所，北京１０００２９为探讨白细胞与血管内皮细胞粘附在哮喘大鼠炎症细胞浸润中的作用，在体观察哮喘大鼠气管微循环中白细胞与细动静脉内皮细胞的粘附。结果表明：（１）...In order to investigate the effect of leukocyte adherence on inflammatory cell infiltration in asthmatic rats. An animal model of asthma is developed, using Wistar rats. The leukocyte adhered to tracheal venular endothelium was assessed by in vivo microscopic observation. The results showed that the number of leukocytes adhered to tracheal venular endothelium increased significantly in asthmatic rats, as compared with those of controls. The smaller of diameter observed was, the more of adherent leukocytes per area of endothelium was. There was no adhered leukocytes on the endothelium of tracheal arterioles. It is concluted that the increase of leukocyte adhered to venular endothelium is pivotal in inflammatory cell infiltration in asthmatic rats.

关 键 词：哮喘 气管微循环 白细胞 粘附 活体观察 

分 类 号：R562.250.2[医药卫生—呼吸系统]