阿立哌唑在住院老年精神疾病患者的临床应用  

Clinical Efficacy of Aripiprazole in the Treatment of Elderly Patients with Mental Disorderse.

作　　者：王占敏[1] 张春长[1] 

机构地区：[1]中国.河北省荣军医院,保定市071000

出　　处：《中国健康心理学杂志》2007年第11期968-969,共2页China Journal of Health Psychology

摘　　要：目的了解阿立哌唑治疗老年期精神障碍患者的用药特点、疗效及锥体外系副反应。方法调查58例以阿立哌唑治疗4周以上、年龄≥60岁的住院老年病人。结果老年病人的平均起始剂量为4.4±1.5mg/d,平均治疗剂量17.5±5.5mg/d,总有效率86.2%,不良反应轻,无明显锥体外系副反应。结论阿立哌唑治疗老年期精神障碍疗效好、剂量低,依从性好,安全性高。Objective To know the application character, efficacy and extrapyramidal side effect （EPS） of aripiprazole in the treatment of late-life psychosis. Methods We investigated 58 case records of elderly inpatients （age≥60 years）. Results For all elderly patients, the average initial dosage was 4.4±1.5mg/d, the average therapeutic dosage was 17. 5±5.5mg/d, the total efficacious rate was 86.2 %, the incidence of EPS was low. The initial dosage and the therapeutic dosage for cerebral organic mental disorder were lower than those for schizophrenia, but the efficacy of cerebral organic mental disorder were better than that of schizophrenia. The therapeutic dosagc wasn＇t different between late-onset schizophrenia and early-onset schizophi-enia. Conclusion For aripiprazolc in the treatment of late-life mental disorders, the efficacy is good, the dosage is low.

关 键 词：阿立哌唑 老年期精神障碍 疗效 剂量 锥体外系副反应 

分 类 号：R592[医药卫生—老年医学]