计算机图像识别技术在超声微泡粒径分析中的应用  

Application of Computer Vision Technique on Quantification of Ultrasound Microbubbles

作　　者：郑元义[1] 张茂惠[1] 彭剑萍[1] 李攀[1] 许川山[1] 冉海涛[1] 王志刚[2] 

机构地区：[1]重庆医科大学附属第二医院超声科,重庆市400010 [2]重庆医科大学超声影像研究所

出　　处：《中国超声医学杂志》2007年第10期727-729,共3页Chinese Journal of Ultrasound in Medicine

基　　金：国家863计划项目(No.2006AA02Z4F0);国家自然科学基金重点项目(No.30430230)

摘　　要：目的探讨计算机图像识别技术在超声微泡粒径分析中的应用价值。方法通过喷雾干燥法制备粉末状脂质超声微泡造影剂,溶于水后在数码显微镜下取不同部位摄像,同时用Malvern粒径分析仪进行微泡粒径测定。应用DFY超声图像定量分析诊断仪的微泡定量功能对所获图像中的微泡进行自动计数与粒径计算。结果DFY型超声图像定量分析诊断仪对微泡的计数与粒径分析结果与Malvern粒径分析仪分析的结果高度吻合;分析结果准确、重复性好。结论DFY型超声图像定量分析诊断仪是国内用于超声微泡计数与粒径分析的一款软件,能够满足科研工作者对微泡粒径分析的需要。Objective To explore the value of computer vision techniques on the analysis of ultrasound microbubbles. Methods Lipid Microbubbles were perpared using spray-dried method. The pictures of the microbubbles were taken using digital microscope. DFY software as well as the Malvern equipement was used for the analysis of the microbubbles distribution. Results The diameters of the microbubbles measured by DFY software were well correlated with the result measured by Malvern equipment. Conclusions DFY software, the first microbubbles counter software, is well designed in analyzing ultrasound images, which can satisfy the needs of the researchers in the analysis of ultrasound microbubbles.

关 键 词：DFY超声图像定量分析诊断仪 计算机图像识别 超声微泡 粒径分析 

分 类 号：R445.1[医药卫生—影像医学与核医学]