微波辐射下5,7-二硝基-8-羟基喹啉的合成  

The synthesis of 5,7-dinitro-8-hydroxyquinoline under microwave irradiation

作　　者：朱惠琴[1] 

机构地区：[1]淮阴师范学院化学系,江苏淮安223001

出　　处：《化学试剂》2007年第10期623-624,627,共3页Chemical Reagents

基　　金：淮安市科技发展计划项目(HAG06051);江苏省高校自然科学研究项目(05KJD150041)资助

摘　　要：在微波辐射下,8-羟基喹啉与硝酸铈铵在乙腈和聚乙二醇溶液中反应生成5,7-二硝基-8-羟基喹啉。最佳反应条件为n(8-羟基喹啉)∶n(硝酸铈铵)=1∶1.3,反应时间6min,5,7-二硝基-8-羟基喹啉的产率达76.2%。The nitration of 8-hydrexyquinoline was carried out with cerium ammonium nitrate in aeetonitrile and polyethylene glycol under microwave irradiation. The results showed that when the molar ratio of 8-hydroxyquinoline to cerium ammonium nitrate was 1 ： 1.3, and the reaction time was 6 min, the yield of 5,7- dinitro-8-hydroxyquinoline was 76.2 %.

关 键 词：8-羟基喹啉 硝酸铈铵 5 7-二硝基-8-羟基喹啉 硝化反应 

分 类 号：O626.32[理学—有机化学]