慢性乙肝患者血清自身抗体检测的临床意义  

Clinical significant for detection of serum autoantibodies in patients with chronic hepatitis B

作　　者：周力[1] 王长嘉[1] 路洪艳[1] 陈阳[1] 王亮[1] 

机构地区：[1]吉林省人民医院肝病科,长春130021

出　　处：《中国卫生检验杂志》2007年第9期1662-1662,1708,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:评价慢性乙肝与自身免疫的关系。方法:应用荧光标记测定慢性乙肝患者血清中ANA、AMA、SMA抗体。结果:85例慢性乙肝患者血清中自身抗体阳性率约为32.94%,明显高于健康对照组。HBV DNA阳性组与HBV DNA阴性组自身抗体检出率无显著差异性。结论:在慢性乙肝患者常规诊疗中检测自身抗体,对其诊断、鉴别诊断及治疗具有重要价值。Objective：To estimate the relationship between chronic hepatitis B and autoimmune. Methods：The fluorescence dye was used to detect the ANA,AMA,SMA in serum of patients with chronic hepatitis B. Results：The positive rate of autoantibodies in chronic hepatitis B was higher in comparison with those in normal group （32. 94%, 28/85 ）. There were no remarkable differences between autoantibodies positive group and autoantibodies negative group in HBV DNA. Condusion： Deteetion of serum autoantibodies in patients with chronic hepatitis B has important value in diagnosis, differential diagnosis and treatment.

关 键 词：慢性乙肝 自身抗体 

分 类 号：R512.62[医药卫生—内科学]