主动脉瓣硬化与颈动脉内膜-中层厚度的相关性及其对冠心病的预测价值  

The correlation between aortic valve sclerosis and carotid intima-media thickness and its predictive value for coronary artery disease

作　　者：马承恩[1] 隋树建[2] 公茂磊[1] 马伟红[2] 

机构地区：[1]山东大学第二医院ICU,济南250033 [2]山东大学第二医院心内科,济南250033

出　　处：《中华超声影像学杂志》2007年第9期764-766,共3页Chinese Journal of Ultrasonography

摘　　要：目的探讨主动脉瓣硬化（AVS）与颈动脉内膜-中层厚度（IMT）的相关性及其对冠心病的预测价值。方法对138例可疑冠心病的患者进行超声心动图检查，将其分为AVS组81例和非AVS组57例。两组患者均行颈总动脉超声和选择性冠状动脉造影检查，比较两组间颈动脉IMT及冠心病发病率的差异。结果AVS组与非AVS组患者冠状动脉造影阳性率分别为91.4％和71.9％（P〈0.01）；AVS组与非AVS组患者颈动脉IMT分别为（1.93±0.39）mm和（O.83±0.19）mm（P〈0.001）；不同类型AVS患者的颈动脉IMT比较差异均有统计学意义。结论AVS与颈动脉IMT具有明显的相关性，对可疑冠心病患者是一项有价值的超声预测指标。Objective To study the predictive value of aortic valve sclerosis（AVS） for the presence of coronary artery disease（CAD） and the correlation between AVS and carotid intima media thickness （IMT）. Methods Echocardiography,carotid ultrasonography and coronary angiography were performed for 138 patients who were suspected suffering from CAD,among which 81 subjects were diagnosed as having AVS（AVS group） , and 57 subjects as non-AVS （N-AVS group）. Carotid IMT and morbidity of CAD were compared respectively between two groups. Results The morbidity of CAD of the two groups was 91.4% and 71.9%, respectively （P 〈 0.01） ;the carotid IMT of the two groups was （1.93±0.39）mm and （0.83±0.19）mm,respectively （P 〈 0. 001）. There were significant differences in carotid IMT among the subjects with each type of AVS [carotid IMTs in subjects with type Ⅰ ,type Ⅱ,type Ⅲ and type Ⅳ AVS was （1.32±0.19）mm,（1.60±0.32）mm, （2.29±0.06）mm, （3.01±0.16）mm,respectively, P 〈0.05 for type Ⅱ vs type Ⅰ , P 〈0.05 for type Ⅲ vs type Ⅱ, P 〈0.01 for type Ⅳ vs type Ⅲ] . Conclusions Carotid IMT is significantly greater in subjects with AVS than in those without AVS. There is a significant correlation between the different grade of AVS and carotid IMT. AVS is a valuable echocardiographic marker for diagnosis of CAD.

关 键 词：超声心动描记术 冠状动脉疾病 主动脉瓣 动脉硬化 颈动脉 

分 类 号：R686[医药卫生—骨科学]