加替沙星治疗社区获得性肺炎的临床效果及不良反应评价  

Evaluating the clinical effect and safety of gatifloxacin in the treatment of community acquired pneumonia

作　　者：郑芙林[1] 郭兆军[2] 

机构地区：[1]安徽理工大学医学院药理学教研室,安徽省淮南232001 [2]安徽淮南市第一人民医院内科

出　　处：《中国基层医药》2007年第8期1254-1255,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的评价加替沙星治疗社区获得性肺炎的临床效果和安全性。方法选择社区获得性肺炎94例,分为治疗组(加替沙星组)和对照组(左氧氟沙星组)。治疗组给予加替沙星200 mg加入5%葡萄糖注射液250 ml静脉滴注,每天2次,共7～10 d;对照组给予左氧氟沙星200 mg,加入5%葡萄糖注射液250 ml静脉滴注,每天2次,共7～10 d。对两组治疗社区获得性肺炎的效果和不良反应进行观察。结果加替沙星组总有效率94%,不良反应发生率8%;左氧氟沙星组总有效率91%,不良反应发生率11%。两组总有效率比较差异无统计学意义(P>0.05)。结论加替沙星治疗社区获得性肺炎,疗效可靠,安全性较好。Objective Evaluating the clinical effect and safety of gatifloxacin in the treatment of community acquired pneumonia. Methods Chose the community acquired pneumonia 94 cases and were divided into a treatment group（gatifloxacin group） and a contrast group（levofloxacin group）. The treatment group were given gatifloxacin for 7-10 days. The contrast group were given levofloxacin for 7- 10 days. Observed the effect and safety of the two group in the treatment of community acquired pneumonia. Results The efficacy rate of gatifloxacin group was 94%, incidence rate of adverse reaction was 8 % ; the efficacy rate of levofloxacin group was 91% and incidence rate of adverse reaction was 11%. No stastistic difference was shown between the two groups for the efficacy rate（ P 〉 0.05 ）. Conclusion Gatifloxation is safe and efficient in the treatment of community acquired pneomonia.

关 键 词：加替沙星 社区获得性肺炎 药物评价 

分 类 号：R563.1[医药卫生—呼吸系统]