人体组织厚度对体外冲击波碎石焦点位置及声压影响的仿真研究  

Simulation of human tissue thickness influence on focal position and sound pressure in ESWL

作　　者：菅喜岐[1] 史启铎[2] 谭中[2] 李文龙[1] 吴立顺[1] 

机构地区：[1]天津医科大学生物医学工程系,300070 [2]天津医科大学第二医院,300211

出　　处：《国际生物医学工程杂志》2007年第4期193-196,共4页International Journal of Biomedical Engineering

基　　金：教育部科学技术研究重点项目基金资助（205006）;教育部留学回国人员科研启动基金资助项目

摘　　要：目的研究体外冲击波碎石（extracorporeal shock wave lithotropisy，ESWL）治疗中不同厚度人体组织对ESWL焦点区域声压及实际形成焦点位置的影响，为ESWL治疗计划的制定提供理论依据。方法以Reichenberger的ESWL水中实验为例，建立三维仿真模型，用时域有限差分（finite differencetime domain，FDTD）数值仿真法，数值仿真ESWL治疗中形成的焦点区域。结果高强度聚焦超声波在人体脂肪、肌肉层非线性传播过程中形成的实际焦点位置和焦点区域声压，随着人体脂肪及肌肉层厚度的变化而变化。结论ESWL治疗过程中由于人体组织厚度的不同，超声非线性传播而形成的焦距和最大声压不同，对于不同体态的患者，在ESWL治疗时应该采用不同的焦距设定方法。Objective Influence on focal position and sound pressure in ESWL （Extracorporeal Shock Wave Lithotropisy） treatment caused by different thickness of human tissue is studied to provide theoretic support for treatment plan. Methods A 3D simulation model is made as an example according to Richenberger＇ s ESWL experiment setup in water. FDTD （Finite Difference Time Domain） method is carried out to simulate a focal region formed by ESWL treatment. Results Actual focal position and sound pressure formed by high intensity focused ultrasonic pulse of nonlinear propagation in human body tissues changes with thickness of human body tissues. Conclusion Because focal position and the maximal sound pressure change with thickness of human tissues, different means of focusing are necessary to be introduced when patients of different bodily form are treated with ESWL.

关 键 词：体外冲击波碎石 脉冲超声波的非线性传播 时域有限差分解析 焦点位置 

分 类 号：R3[医药卫生—基础医学]