颗粒状脂肪组织移植的实验研究  

Experimental study on free grafting of fat particles

作　　者：祁佐良[1] 李二恪[2] 王厚滨 张威 王炜[1] 张涤生[1] 

机构地区：[1]上海第九人民医院整形外科 [2]大连理工大学职工医院 [3]佳木斯医学院

出　　处：《中华整形烧伤外科杂志》1997年第1期54-56,84,共3页

摘　　要：为进行颗粒状脂肪组织移植后变化的研究,选用大鼠48只,通过对应用胰岛素处理、体积测量、墨汁灌注、光镜和电镜进行观察。结果表明,胰岛素实验组与对照组的体积变化无显著性差异,移植后体积明显减少,达44.6%。移植早期缺血,脂肪细胞释放脂类,逆行性分化为成脂肪细胞。血运建立以后,成脂肪细胞不断吸收合成脂类,逐渐分化为成熟的脂肪细胞。6个月后移植物的组织结构接近正常。超微结构发现微丝状的网状结构是形成脂滴的支架,与脂类的合成有密切关系。Forty-eight rats were used to study the change in fat tissue after grafting.In the experi- mental group,the fat tissue to be grafted was treated with insulin.Evaluation was made by graft mea- surement,ink injection,light microscopic and electronic microscopic observations.The results showed that the volume of the grafted fat decreased obviously and there was no significant difference between the experimental and the control groups in the change of volume of the grafted fat tissue.At the early stage of grafting,the grafted fat showed ischemia.The adipocytes released lipid and dedifferentiated to preadipocytes.After revascularization,the preadipocytes began to absorb lipid and became mature adipocytes.The structure of the grafted fat was almost normal at 6 months after grafting.The formation of the cytoskeletal filament,found by ultrastructural study,was closely related with the synthesis of lipid.

关 键 词：脂肪细胞 颗粒状脂肪组织 实验 移植 

分 类 号：R622.9[医药卫生—整形外科]