挥发性吸入麻醉药对肺的作用  

The effects of inhaled anesthetics on lung

作　　者：上官王宁[1] 刘进[1] 

机构地区：[1]四川大学华西医院麻醉科

出　　处：《国际麻醉学与复苏杂志》2007年第4期320-322,共3页International Journal of Anesthesiology and Resuscitation

摘　　要：挥发性吸入麻醉药对肺的作用目前尚未有定论,其中有较多争议之处。不同种类、不同吸入浓度以及不同生理条件下的吸入麻醉药对肺的作用不同,可以引起肺的损伤作用、导致肺内分流增加,也可以产生肺的缺血/再灌注损伤的保护作用,其机制尚未完全清楚。The final conclusion for the effects of inhaled anesthetics on the lung has not been obtained yet, leaving some issues to debate. Their effects are different for different inhaled anesthetics, different inhaled concentration, and different physiological condition. In one hand inhaled anesthetics could cause injury effect on the lung by causing pulmonary surfactant reduction and an increase in lung shunt rate; on the other hand inhaled anesthetics could produce protective effect for ischemic - reperfusion injury of lung because of their anesthetic preconditioning, although their mechanisms remain unclear.

关 键 词：吸入麻醉药 肺 缺血 再灌注损伤 效应 

分 类 号：R614[医药卫生—麻醉学]