肝移植术后侵袭性肺曲霉病的个体化治疗  

Individualized treatment of invasive pulmonary aspergillosis after liver transplantation

作　　者：张中伟[1] 康焰[1] 王文涛[2] 周琰[1] 杨加印[2] 罗传兴[1] 严律南[2] 

机构地区：[1]四川大学华西医院ICU,四川成都610041 [2]四川大学华西医院普外科,四川成都610041

出　　处：《中国呼吸与危重监护杂志》2007年第5期356-359,共4页Chinese Journal of Respiratory and Critical Care Medicine

摘　　要：目的探讨肝移植术后侵袭性肺曲霉病的个体化治疗方案。方法回顾性分析2004年1月～2006年12月期间12例肝移植术后侵袭性肺曲霉病患者的临床表现、治疗方案、并发症及预后。结果12例患者死亡5例,病死率41.7%,治疗效果较既往得到改善。结论肝移植术后侵袭性肺曲霉病的治疗需要根据患者情况选择抗曲霉菌药物,进行免疫抑制剂的个体化调整。Objective To explore individualized treatment of invasive pulmonary aspergillosis after liver transplantation.nethods The clinical manifestation, treatment, complication and prognosis of 12 patients with invasive pulmonary aspergillosis after hver transplantation from 2004 to 2006 were analyzed. Results Five patients died with a mortality rate of 41.7%. Therapeutic efficacy was improved obviously by individualized Anti-aspergillus drugs and immunosuppressive agent should be individuahzed on the basis of the patients＇ condition. Meanwhile combined therapy is essential.

关 键 词：肝移植 侵袭性肺曲霉病 个体化 

分 类 号：R657.3[医药卫生—外科学] R519[医药卫生—临床医学]