白芷挥发油GC指纹图谱研究  

Studies on the GC fingerprint of essential oils from Radix Angelicae Dahuricae

作　　者：王婷婷[1] 李清[1] 宋爱华[1] 陈晓辉[1] 毕开顺[1] 

机构地区：[1]沈阳药科大学药学院,沈阳110016

出　　处：《药物分析杂志》2007年第9期1340-1343,共4页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:建立白芷挥发油成分的 GC 指纹图谱。方法:SE-30毛细管气相色谱柱(30 m×0.25 mm×0.25 μm),FID 检测器,程序升温为70℃(5 min),以2℃·min^(-1)的速度线性升温至220℃(5 min)。结果:依据21批药材的指纹图谱数据进行聚类分析,将样品分为4类,选定其中10批优质样品建立共有模式。相似度分析结果表明,第Ⅰ类和第Ⅱ类样品为优质药材,第Ⅲ类样品质量一般,第Ⅳ类样品为伪品。结论:本测定方法为白芷药材的质量评价提供了科学依据。Objective：To establish the GC fingerprint of essential oils from Radix Angelicae Dahuricae. Method： The measurement conditions applied were as follows ： SE - 30 capillary column （ 30 m × 0.25 mm × 0. 25 μm）, FID detector and the temperature of column was increased linearly from 70 ℃ （5 min） to 220 ℃ （5 min）, at a speed of 2 ℃ · min^-1. Results：The 21 samples were classified as 4 grades by cluster analysis and the 10 superior in producing area samples were confirmed to establish the mutual models. The result of similarity analysis showed that the grade Ⅰ and Ⅱ were commendatory, the grade Ⅲ was general, and the grade Ⅳ was spurious. Conclusion： The method is reliable to evaluate the quality of Radix Angelicae Dahuricae.

关 键 词：白芷 挥发油 GC指纹图谱 

分 类 号：R917[医药卫生—药物分析学]