儿童亚急性坏死性淋巴结炎23例临床分析  

Clinical analysis for 23 cases with subacute necrotizing lymphadenitis

作　　者：王巧伟[1] 陈淑君[1] 

机构地区：[1]浙江省义乌市中心医院儿科,义乌322000

出　　处：《临床医学》2007年第10期16-17,共2页Clinical Medicine

摘　　要：目的探讨亚急性坏死性淋巴结炎的病因、临床特征和实验室检查特点,以提高对亚急性坏死性淋巴结炎的认识。方法回顾性分析23例经病理确诊的临床病例。结果发病以学龄儿为主,平均年龄(8.8±2.3)岁,男女之比2∶3。临床主要表现为发热、淋巴结肿大、白细胞减少;抗EB病毒抗体阳性率高;21例给予肾上腺皮质激素治疗,效果显著。结论对于不明原因发热伴淋巴结肿大疼痛者,应尽早行淋巴结活检确诊,该病呈自限性,糖皮质激素治疗有效,但少数有复发,发展为系统性红斑狼疮可能,应长期随访。Objective To investigate etiological factors, clinical characteristic and related laboratory findings of subacute necrotizing lymphadenitis and improve the acknowledgement of subacute necrotizing lymphadenitis. Methods Retrospective analyzed 23 cases of subacute necrotizing lymphadenitis diagnosis by lymph node biopsy. Results Most of these were school children with a mean age of （ 8, 8 ± 2.3 ） years. The ratio of male to female was 2： 3, Clinical presentation includes fever, lymphadenapathy and leueocytopenia, Serum antibody of EB virus was positive in 20 cases, Corticoid therapy in 21 cases showed good outcome. Conclusion Subacute necrotizing lymphadenitis should be considered when children with fever and swelling and painful lymphadenopathy. Lymph node biopsy is the only way to confirm the diagnosis, The process is self - limited and effective with glucoeortieoids therapy. The follow up is required as recurrence and development of systemic lupus erythematosus have reported.

关 键 词：亚急性坏死性淋巴结炎 淋巴结病 发热 抗EB病毒抗体 

分 类 号：R725.5[医药卫生—儿科]