健康傣族人CD_3^+CD_4^+和CD_8^+T淋巴细胞绝对数正常值调查  

Normal reference ranges of CD_3^+CD_4^+ and CD_8^+ in healthy Dai ethnics in DeHong prefecture

作　　者：段松[1] 项丽芬[1] 马罗云[1] 叶润华[1] 段启祥[2] 刘志远[3] 康永然[4] 段一娟[5] 濮永成[2] 王斌[3] 杨建华[4] 李维美[6] 韩文香[2] 杨忠桔[5] 邓丽华[1] 李艳玲[1] 王继宝[1] 杨跃诚[1] 

机构地区：[1]德宏州疾病预防控制中心,云南潞西678400 [2]陇川县疾病预防控制中心,云南陇川678700 [3]潞西市疾病预防控制中心,云南潞西678400 [4]盈江县疾病预防控制中心,云南盈江679300 [5]瑞丽市疾病预防控制中心,云南瑞丽678600 [6]梁河县疾病预防控制中心,云南梁河679200

出　　处：《中国艾滋病性病》2007年第5期424-426,共3页Chinese Journal of Aids & STD

基　　金：中国疾病预防控制中心性病艾滋病预防控制中心参比实验室资助

摘　　要：目的了解德宏州健康傣族人群外周静脉血CD3+、CD4+、CD8+T淋巴细胞绝对数和CD4+/CD8+比值的正常值范围。方法应用流式细胞仪(FACSCount)检测253例健康傣族人的CD3+、CD4+、CD8+T淋巴细胞绝对数和CD4+/CD8+比值,并观察以上数值在性别和年龄上的差异。结果CD3+、CD4+、CD8+和CD4+/CD8+的正常值参考范围分别为(1 543±443)个/μl(、849±261)个/μl(、567±225)个/μl和1.63±0.55。CD3+、CD4+在性别和年龄组别间的差异均无统计学意义,而CD8+和CD4+/CD8+在年龄组别间的差异有统计学意义。结论初步建立了健康傣族人群CD3+、CD4+、CD8+和CD4+/CD8+的正常值参考范围,对于指导德宏州艾滋病的诊断及治疗工作有重要意义。Objective To establish absolute value of CD3^＋ ,CD^＋, CD8^＋ and normal reference ranges of CD4^＋/CD8^＋ ratio in healthy Dai ethnics in DeHong prefecture. Methods Blood samples from 253 healthy Dai people were used for this study,and lymphocyte subsets were analyzed by FACSCount Flow Cytometer. Results Normal reference ranges were as follows：CD3^＋- 1 543 ± 443/td;CD4^＋ - 849±261/μl;CD8^＋ - 567 ± 225/μl;CD4^＋/CD8^＋ - 1.63± 0.55.No difference was found in CD3^＋ , CD4^＋ , CD8^＋ values and CD4^＋/CD8^＋ ratio between genders;while there was significant difference in CD8^＋ value and CD4^＋/CD8^＋ ratio among different age groups. Conclusion CD4^＋ value in this study is similar to those in American and Henan healthy people, but higher than those in Shanghai. The normal reference ranges of CD3^＋ , CD^＋, CD8^＋ and CD4＋ / CDs＋ ratio are thus established for Dai ethnics, which will provide important information for HIV/AIDS diagnosis and treatment in DeHong prefecture.

关 键 词：傣族 CD4^+ T淋巴细胞 CD8^+ T淋巴细胞 正常值参考范围 

分 类 号：R512.91[医药卫生—内科学] R392.12[医药卫生—临床医学]