额叶皮层对丘脑中央外侧核神经元针刺镇痛效应的下行性影响  

DESCENDING INFLUENCE OF FRONTAL LOBE CORTEX ON ACUPUNCTURE ANALGESIA INVOLVING CENTRALIS LATERALIS NEURONS OF THE THALAMUS

作　　者：高美兰[1] 张均明[1] 李倩茗[1] 刘荫仁[1] 

机构地区：[1]广西医学院生理学教研室针麻研究室

出　　处：《广西医学院学报》1990年第1期65-69,共5页

摘　　要：本文进一步研究额叶皮层对中央外侧核(Centralis Lateralis,CL)神经元针刺镇痛效应的下行性影响。观察在额叶皮层局部应用2%利多卡因后,电针对中央外侧核神经元伤害性反应的影响。结果表明,应用2%利多卡因之前,大部分CL神经元的伤害性反应被电针所抑制(25/27)。但应用2%利多卡因之后,电针的抑制效应被削弱(4/26)。在2%利多卡因组与单纯电针组之间有统计学意义(P<0.01),在单纯电针组与盐水组之间无统计学意义(P>0.05)。In the present study,the descending influence of frontal lobe cortex on acupuncture analgesia effect in Centralis Lateralis(CL)was further investigated.The effect of electroacupuncture on the nociceptive response of CL neurons after topical administration of 2% Lidocaine was observed. The results indicated that before the administration of 2% Lidocaine, the nociceptive response of the majority of the CL neurons were inhibited by electroacupuncture(25/27).However,such electroacupuncture inhibitive effect was reduced by 2% Lidocaine(4/26),and there exist statistical significance between the 2% Lidocaine group and the simple electroacupuncture group (P>0.01),but there was no statistical significance between the simple electroacupuncture group and the saline group(P>0.05).

关 键 词：额叶皮层 中央外侧核 针刺镇痛 

分 类 号：R245.97[医药卫生—针灸推拿学]