吉林省2006年麻疹减毒活疫苗应急免疫效果评价  

Evaluation of Measles Emergency Vaccination in Jilin Province in 2006

作　　者：陈超[1] 周剑惠[1] 田鑫[1] 郑文毅[1] 林琳[1] 张运祥[1] 曹凤瑞[1] 李大强[1] 刘影[1] 王爽[1] 常新[1] 程涛[1] 韩春莉[1] 

机构地区：[1]吉林省疾病预防控制中心,长春130062

出　　处：《中国计划免疫》2007年第5期429-432,共4页Chinese Journal of Vaccines and Immunization

摘　　要：目的评价吉林省2006年实施麻疹减毒活疫苗（MV）应急免疫效果，为消除麻疹策略提供依据。方法利用麻疹病原学监测资料、MV应急免疫接种率资料、人群麻疹抗体资料、2006年疫情网络直报和麻疹监测系统资料，综合分析MV应急免疫效果。结果吉林省2006年麻疹流行病毒为H1基因型，MV应急免疫报告接种率为96．76％，快速评估接种率为98．20%，应急免疫后人群麻疹IgG抗体阳性率为97．6％，发病率显著下降。结论对8月龄～14岁人群进行MV应急免疫，能迅速形成有效的免疫屏障，阻断麻疹病毒传播，降低麻疹发病。Objective To summarize the effect of measles emergency vaccination campaign in Jilin Province and to provide evidence for strategies and measures of measles prevention and control. Methods The effect of measles emergency vaccination campaign was analyzed comprehensively, including the surveillance information of measles pathogeny, vaccination rate of measles emergency vaccination campaign, the information of measles antibody, the information of net-directing reporting system of infectious diseases-based information of measles surveillance system. Result The genotype of circulating measles virus was H1, total reported coverage was 97.76 %, total coverage of rapid evaluation was 98.20% ,the positive rate of measles IgG antibody after emergency vaccination campaign was 97.6 %, the morbidity decreased remarkably. Conclusion Measles cases 8--14 years old decreased remarkably after emergency vaccination campaign of. The key for successful activities was to arrange the area, object, aim and schedule well, to do the prevaccination preparation and vaccination-site implementation,to establish effective immunity barrier to interrupt the virus transmission within the shortest time （14 days）.

关 键 词：麻疹减毒活疫苗 应急免疫 效果评价 

分 类 号：R186[医药卫生—流行病学] R511.1[医药卫生—公共卫生与预防医学]