β-(3,5-二叔丁基-4-羟基苯基)丙酰氯的合成研究  

Synthesis of β-(3,5-Diterbutyl-4-hydroxyphenyl) Propionyl Chloride

作　　者：王俊[1] 张会平[1] 李翠勤[1] 杨洪军[1] 邸晓贺[1] 

机构地区：[1]大庆石油学院化学化工学院,黑龙江大庆163318

出　　处：《精细化工中间体》2007年第5期61-63,共3页Fine Chemical Intermediates

基　　金：黑龙江省教育厅科研项目(10551007)。

摘　　要：以β-(3,5-二叔丁基-4-羟基苯基)丙酸甲酯为原料,通过水解反应和酰氯合成反应合成了抗氧剂中间体β-(3,5-二叔丁基-4-羟基苯基)丙酰氯。对酰氯合成条件进行了研究,得出优惠反应条件为:以氯仿作溶剂、β-(3,5-二叔丁基-4-羟基苯基)丙酸0.02mol、二氯亚砜0.054mol、反应温度50℃、反应时间5h,优惠条件下产品的收率为98.9%。β-（3,5-Diterhutyl-4-hydroxyphenyl） propionyl chloride is synthesized with 3,5-methyl propionate as raw material via hydrolytic reaction and replacement reaction, and the replacement reaction conditions were explored. The optimal reaction conditions were as follows： chloroform was used as the reaction solvent, 3,5-propionyl acid 0,02 mol, sulphoxide diloride 0.054 mol, the reaction temperature 50℃ and the reaction time 5 h. Under these conditions, the yield of product was 98.9%.

关 键 词：β-(3 5-二叔丁基-4-羟基苯基)丙酸甲酯 β-(3 5-二叔丁基-4-羟基苯基)丙酸 β-(3 5-二叔丁基-4-羟基苯基)丙酰氯 抗氧剂中间体 合成 

分 类 号：TQ314.249[化学工程—高聚物工业]