食管癌患者手术治疗前后血清NO/NOS、CEA和SIL-2R测定的临床意义  

Clinical Significance of Determination of Post-Operative Changes of Serum NO/NOS,CEA and SIL-2R Levels in Patients with Esophageal Cancer

作　　者：姚永良 

机构地区：[1]江苏省昆山市第一人民医院放免科,215300

出　　处：《放射免疫学杂志》2007年第5期407-409,共3页Journal of Radioimmanology

摘　　要：目的:探讨了食管癌患者手术治疗前后血清NO/NOS、CEA和SIL-2R水平的测定及临床意义。方法:分别应用放射免疫分析、化学法和酶联免疫分析测定了33例食管癌患者血清NO/NOS、CEA和SIL-2R含量,并与35名正常健康人作比较。结果:手术前食管癌患者血清NOS、CEA和SIL-2R水平非常显著地高于正常人组(P<0.01),而NO水平则低于正常人组(P<0.01),经治疗后3个月则与正常人组比较无显著性差异(P>0.05)。结论:检测食管癌患者血清NO/NOS、CEA和SIL-2R水平的变化对观察病情和预后判定具有重要的临床价值。Objective To study the significance of post - operative changes of serum NO/NOS, CEA and SIL - 2R levels in patients with esophageal cancer. Methods Serum CEA （with RIA）, SIL -2R （with ELISA） and NO/NOS （with chemistry） levels were determined both before and after operation in 33 patients with esophageal cancer and 35 controls. Results Before operation, sertum NOS, CEA and SIL- 2R levels in the patients were significantly higher than those in controls （P 〈 0.01 ）, while serum NO levels was lower than those in controls （ P 〈0.01 ）. Three months after operation the differences were not significant （ P 〉 0.05 ）. Conclusion Changes of serum NO/NOS, CEA and SIL - 2R contents after operation might be of prognostic importance in patients with esophageal cancer.

关 键 词：食管癌 一氧化氮 一氧化氮合成酶 癌胚抗原 白细胞介素-2受体 

分 类 号：R446.61[医药卫生—诊断学]