绒毛膜羊膜炎与早产儿脑损伤的相关性研究  

The relationship between maternal chorioamnionitis and brain injury of preterm infants

作　　者：章丽丽[1] 郁敏[1] 夏钰弘[1] 吴伟燕[1] 

机构地区：[1]江苏省无锡市第五人民医院,214073

出　　处：《中国优生与遗传杂志》2007年第10期79-80,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨早产儿脑损伤与母亲绒毛膜羊膜炎的关系。方法选取2005年10月到2006年10月在我院出生的早产儿共98例。根据胎盘病检结果分为有绒毛膜羊膜炎组(41例)和无绒毛膜羊膜炎组(57例)。所有病例在生后3～7天内进行头颅B超检查,并在纠正胎龄40周时予NBNA(新生儿行为神经测定)评分。通过B超及NBNA评分观察两组脑损伤的发生情况。结果孕母有绒毛膜羊膜炎的早产儿脑损伤的发生率达39.02%,NBNA得分35.36±2.55,与对照组相比,差异显著(P<0.05)。结论绒毛膜羊膜炎与早产儿脑损伤的发生有一定关系。Objective： To explore the relationship between maternal chorioamnionitis and the brain injury in preterm infants, Methods： 98 preterm infants were selected from Wuxi Municipal Fifth People＇s Hospital from October 2005 to October 2006. The cases were divided into two groups according to the results of histological methods. Infants with maternal chorioamnionitis is 41, the control group is 57, Totally infants were checked by head ultrasonography from 3 - 7days after born and were scored by the Neonatal Behavioral Neurological Assessment （NBNA） after correcting age 40 weeks. To observe the occurrence of the brain injury of preterm infants in two groups, Results： The case rate of brain injury in the group with maternal chorioamnionitis is 39.2% , NBNA score 35.36 ± 2, 55, which is significantly higher than the control group＇s , （ P 〈 0. 05 ）. Conclusion： The maternal Chorioamnionitis is associate with the brain injury of preterm infants.

关 键 词：绒毛膜羊膜炎 早产儿 脑损伤 新生儿行为神经测定 

分 类 号：R722.6[医药卫生—儿科]