鼠疫F1单克隆抗体腹水制备过程中的影响因素分析  

Analysis of Influential Factors in Ascites Preparation of F1 Antibody of Yersinia pestis

作　　者：杜春红[1] 王鹏[1] 钟佑宏[1] 陈平[1] 尹家祥[1] 于国林[1] 

机构地区：[1]云南省地方病防治所,云南大理671000

出　　处：《地方病通报》2007年第6期5-6,共2页Endemic Diseases Bulletin

基　　金：国家自然科学基金项目(30160078);云南省科技攻关计划资助项目(2002NG17)

摘　　要：目的分析制备鼠疫F1单克隆抗体腹水中的一些影响因素。方法收集课题组在制备腹水过程中的相关资料并进行分析。结果腹水的制备受小鼠、免疫抑制剂、杂交瘤细胞的性状、腹水的采集与处理等方面因素的影响。结论通过采取一些措施,可以适当提高鼠疫F1单克隆抗体的腹水质量。Objective To analyze influential factors in ascites preparation of F1 antibody of Yersinia pestis. Method Relative materials in preparation of F1 antibody ascites were collected and analyzed. Results Ascites preparation is influenced by mice, immunosuppressor, hybridoma, ascites collection and disposal, and so on. Conclusions The quality and quantity of ascites can be improved by adopting some measures.

关 键 词：鼠疫 单克隆抗体 腹水 影响因素 

分 类 号：R378.61[医药卫生—病原生物学]