热毒净及阿昔洛韦对EB病毒抗原表达抑制作用的对比实验  

The contrasting experiment to the inhibition of Redujing and Acyclovir on EB virus antigen expression

作　　者：刘晓红[1] 叶树清[2] 周玲[2] 张忠浩[1] 刘力戈[1] 杨春霞[1] 郑杨[1] 王新佳[1] 王绮[2] 

机构地区：[1]首都医科大学附属北京友谊医院儿科,北京100050 [2]中国预防医学科学院病毒病研究所,北京100052

出　　处：《天津中医药》2007年第5期408-410,共3页Tianjin Journal of Traditional Chinese Medicine

基　　金：北京中医药科技项目资助(JJ2005-7)。

摘　　要：[目的]观察热毒净及阿昔洛韦对EB病毒抗原表达有无抑制作用,并比较两者对EB病毒的作用强弱。[方法]免疫酶法测定热毒净及阿昔洛韦对Raji细胞早期抗原(EA)的表达,分别计算出两者的阻断率(IR)。[结果]热毒净在无毒的浓度下,对Raji细胞EB病毒EA抗原表达有较强的抑制作用,阿昔洛韦在实验的浓度下,对EB病毒EA抗原表达也有抑制作用。[结论]热毒净与阿昔洛韦比较能较强抑制EB病毒抗原的表达。[Objective] To observe the inhibitory effect of Redujing and Acyclovir on EB （Epstein-Barr） virus antigen expression and compare witch is more effective. [Methods] The effect of Redujing and Acyclovir on Raji cell＇ s early antigen（EA） expression was assayed by immunity enzyme technique, and IR is also calculated. [Results] At the non-toxic concentration,Redujing had strongly inhihitory effect on Raji cell EB-virus and Acyclovir also had inhibitory effect on Raji cell EB-virus. [Conclusions] Redujing have more inhibition to EB virus antigen expression than Acyclovir.

关 键 词：热毒净 阿昔洛韦(无环鸟苷) EB病毒 抗原表达 阻断 

分 类 号：R285.5[医药卫生—中药学]