IgA肾病研究进展  

Advancement of IgA Nephropathy

作　　者：王晓亮[1] 王晓丹[1] 白云凯[1] 

机构地区：[1]昆明医学院附属第一医院肾脏科,昆明650032

出　　处：《医学综述》2007年第21期1628-1630,共3页Medical Recapitulate

摘　　要：原发性IgA肾病是世界范围内最常见的肾小球肾炎,是引起终末期肾功能衰竭的重要原因之一。以往认为此病呈良性经过,预后良好,然而近年来的一系列随访研究证实,此病在确诊后5-25年内,有20%-40%的患者发展为终末期肾脏疾病。迄今为止,其发病机制尚不完全明了,临床及病理表现多样,仍无特异性治疗药物,预后各不相同。仅就近年来对该病的研究进展简要综述。Primary IgA nephropathy is the most common glomerulonephritis worldwide, which is the important factor resulting in end stage renal failure. In the past, it is considered to be a benign course with good prognosis. However,a series of follow-up investigations in recent year confirmed that about 20% - 40% patients with IgA nephropathy have developed into end stage renal disease within 5 - 25 years after their final diagnosis. Up to date, its pathogenesis remains poorly understood, its clinical and pathological manifestations present diversities, there is no specific drugs for the treatment of patients with IgA nephropathy and they have different prognosis. This article reviews study progresses related to IgA nephropathy. In recent years.

关 键 词：IGA肾病 肾小球肾炎 流行病学 治疗 预后 

分 类 号：R692.31[医药卫生—泌尿科学]