幽门螺杆菌感染对慢性胃炎患儿胃动力功能的影响  

Effect of Helicobacter Pylori on Gastric Motor Function in Children with Chronic Gastrictis

作　　者：潘彤彤[1] 徐彰[1] 徐辉[1] 周晓青[1] 

机构地区：[1]温州医学院附属育英儿童医院消化内科,浙江温州325027

出　　处：《实用儿科临床杂志》2007年第19期1455-1456,共2页Journal of Applied Clinical Pediatrics

摘　　要：目的探讨幽门螺杆菌(Hp)感染对慢性胃炎患儿胃动力功能的影响。方法通过Hp检测及组织病理检查,将47例慢性胃炎患儿分为Hp阳性和阴性组。对各组进行固体餐放射性核素胃排空检查和胃电图(EGG)检测。Hp阳性患儿予克拉霉素15mg/(kg.d)、阿莫西林50 mg/(kg.d)、奥美拉唑0.8 mg/(kg.d)三联抗Hp治疗2周。其中Hp根除者再行EGG检测。结果Hp阳性组胃半排空时间(GET1/2)明显高于Hp阴性组(t=6.403 P<0.01)。二组EGG参数值比较无明显差异,但Hp阳性组存在餐前振幅不规则现象,且Hp阳性组根除Hp前餐前主功率明显低于根除后(t=2.197 P<0.05)。结论Hp感染影响患儿胃排空及胃肌电活动,导致慢性胃炎患儿胃动力功能低下。Objective To explore the influence of helicobacter pylori（Hp） on gastric motor function in children with chronic gastrictis. Methods Forty - seven children with chronic gastrictis were classified into Hp positive and negative groups according to Hp and histology examination. Each child underwent gastric emptying test of solid by using nuclide method and electrogastrogram（EGG） examination. These cases with Hp - positive acceptted these triple eradication therapy [ clarithromycin 15 mg/（ kg·d）, amoxicillin 50 mg/（ kg ·d ）, omeprazole 0.8 mg/（ kg·d） ] for 2 weeks, and underwent EGG examination again after eradicating Hp. Results The half emptying time（ GET1/2 ） in Hp - positive gastric group were significantly longer than those in Hp - negative group （ t = 6. 403 P 〈 0.01 ）. There was no significant difference in parameters of EGG between 2 groups. But the postprandial amplitude in Hp - positive gastric group showed irregularly, and the postprandial dominant power before Hp eradication were significantly lower than those after Hp eradication （ t = 2. 197 P 〈 0.05 ）. Conclusion Hp infection reduces the gastric motor function in children with chronic gastrictis by influencing gastric emptying and gastric myoelectrical activity.

关 键 词：螺杆菌 幽门 胃动力功能 胃排空 胃电图 胃炎 慢性 儿童 

分 类 号：R725.7[医药卫生—儿科]