肝紫斑病1例并文献复习  

Case Report of Peliosis Hepatic in Child and Its Literature Review

作　　者：覃肇源[1] 陈述枚[1] 胡瑞德[2] 蒋小云[1] 刘美娜[1] 沈振宇[1] 

机构地区：[1]中山大学附属第一医院儿科,广州510080 [2]中山大学附属中山医学院病理学教研室,广州510080

出　　处：《实用儿科临床杂志》2007年第19期1461-1462,1489,共3页Journal of Applied Clinical Pediatrics

摘　　要：目的通过报告1例肝紫斑病(PH),复习文献进行分析讨论。方法对1例以腹痛、肝大1个月为主诉的4岁女童询问病史、体格检查、实验室检查、影像学检查和肝穿刺活组织病理检查(HE染色)。结果4岁女童,起病前曾被虫咬,局部出现红斑、疱疹皮炎,随后出现发热、咳嗽,继以腹痛、肝大、胸腔积液、腹水。实验室检查为天冬氨酸转氨酶、γ-谷氨酰转肽酶和碱性磷酸酶轻度增高。肝B超声和CT检查示肝大,实质密度不均。肝活检见多个充满血液小囊腔。结论本病临床特征为发热、上腹痛、黄疸、肝大,结合肝脏病理活检可诊断本病。Objective To report a peliosis hepatic in child and review literature and discuss. Methods Case history was inquired, Physical,labtoratory, imagement and histopathology of liver biopsy （ HE staining） were examed. Results A 4 - year old girl appeared dermatitis with erythema and herpes at local skin where was bit by insect before onset. The girl appeared fever, cough, then abdominal pain, hepatomegaly, pleural effusion and ascites. Lab examination revealed slight elevation of aspartate transaminase, γ- glutamyltranspeptidase and alkaline phosphatase. The liver B - mode ultrasonography and CT scan revealed hepatomegaly with density heterogeneity of the parenchyma. The liver biopsy revealed many small capsule filled with blood cells. Conclusions Clinical characteristics of the disease are fever, upper abdomen pain, janundice, ascites and hepatomegaly. The diagnosis shall be combined with the pathologic biopsy of liver.

关 键 词：肝穿刺活检 肝紫斑病 病理 诊断 

分 类 号：R725.7[医药卫生—儿科]