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出 处:《旅行医学科学》2007年第3期39-41,共3页
基 金:本文受国家质检总局2006年科研项目<口岸传染病媒介的定量风险分析及建立早期预警反应系统>资助。
摘 要:目的采用Meta分析方法探讨出入境人员中HBsAg携带率在不同年龄组之间的差异,为确定重点监测人群提供科学依据。方法以多个独立研究的率差RD值为效应指标,对资料进行异质性检验,以确定采用固定或随机效应模型进行分析;采用漏斗图法检验发表偏倚。结果共收集2003.1~2006.7年间国内公开发表的相关文献9篇,经异质性检验,采用随机效应模型计算合并RD值为-0.02(95%CI-0.03~-0.01,Z=3.31,P<0.01)。结论出入境人员中年龄>30岁组HBsAg携带率高于≤30岁年龄组,这一人群应作为今后的检测重点。Objective To assess the diversity of HBsAg in different age groups through a meta analysis, in order to provide scientific evidence for surveillance. Methods The rate difference (RD) was considered as the effect size. According to the results of heterogeneity test, a fixed effect model or a random effect model was used. The publication bias was tested by funnel pot. Results Nine published papers were included in the meta analysis, and the pooled estimate of rate difference was -0.02 (95% CI -0.03~-0.01, Z=3.31, P〈0.01). Conclusions The HBsAg positive rate was much higher if the international travelers were older the thirty. So we should pay more attention to this population in the future work.
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