激光共焦扫描显微镜中的图像复原方法  

A Image Restoration Method for Laser Confocal Scanning Microscopy

作　　者：黄琳[1] 陶纯堪[1] 胡茂海[1] 

机构地区：[1]南京理工大学电光学院,南京210094

出　　处：《光子学报》2007年第4期642-644,共3页Acta Photonica Sinica

摘　　要：在非负值和有限支撑域的递归逆滤波(NAS-RIF)盲图像复原算法的基础上,根据激光共焦扫描显微镜(LCSM)采集到的图像特点,提出了改进方法.首先对LCSM采集到的显微图像进行高斯滤波以提高退化图像的信噪比,然后进行局部直方图均衡以突出显微图像的细节,最后在代价函数中加入空间自适应正则化项,较好地恢复了具有丰富细节信息的显微图像.　The laser confocal scanning microscopy （LCSM） system is a kind of modern microscopic instruments which is characterized by its depth discrimination capability.Theories and methods of how to restore the microscopic image based on the improved NAS-RIF algorithm were discussed.Firstly,the denoising technique was used to increase the SNR.Then the histogram equalization was used to preserve the edge feature of the degraded image.In the end,a developed cost function was used to prevent noise amplification.The experiment results show that the reconstructed images have high quality.

关 键 词：激光共焦扫描显微镜 图像复原 NAS-RIF算法 

分 类 号：TN911.73[电子电信—通信与信息系统]