0.75%布比卡因和0.75%左旋布比卡因用于术后硬膜外止痛的观察  

A clinical comparison of 0.75%Bupivacaine and 0.75% Levobupivacaine in epidural analgesia afer operation

作　　者：孙晓娟[1] 王仿[1] 张彦声[1] 

机构地区：[1]西安市红十字会医院麻醉科,西安710054

出　　处：《陕西医学杂志》2007年第6期726-727,共2页Shaanxi Medical Journal

摘　　要：目的：比较0.75%布比卡因和0.75%左旋布比卡因用于术后硬膜外止痛的的镇痛效果与安全性.方法：选择ASA分级Ⅰ～Ⅱ级下肢手术接受术后硬膜外镇痛的病人50例,随机分为2组：A组（n=25）用0.75%布比卡因;B组（n=25）用0.75%左旋布比卡因行术后硬膜外自控镇痛,观察患者12h、24h和48h的镇痛效果、镇痛满意程度、各组药物需求量（PCA按压次数×0.5ml）以及有关的副作用.结果：两组均可达到完善的镇痛效果,均无剧痛病例,B组药物需求量（PCA按压次数×0.5ml）多于A组（P＜0.05）,均未见局麻药毒性反应和并发症.结论：0.75%布比卡因用于术后硬膜外镇痛,其镇痛效果优于0.75%左旋布比卡因.Objective： To compare the effects and safety of 0. 75% bupivaciane and 0. 75% Levobupivacaine in epidural analgesia afer operation. Mehtods： 50 ASA Ⅰ～Ⅱ adults scheduled for lower extremity or Lower limb surgery were divided into two groups. Group A, and B （n= 25 in each group） received 0. 75%bupivacaine and 0. 75% levobupivacaine respectively for PCEA. The analgesia effect , satisfaction degree, medicine demand （number of PCEA attack × 0. 5ml） and related side effect were observed at that time 12h , 24h and 48h. Results. Each group obtained satisfactory analgesia effect . Medicine demand of group B（number of PCEA attack × 0. 5ml）was more than group A（P〈0. 05）. There appeared no toxic responses and mplications. Conclusion： The effect of 0. 75% bupivacaine in epidural analgesia is superior to 0. 75%levobupivacaine.

关 键 词：镇痛 硬膜外 布比卡因 术后硬膜外止痛 

分 类 号：R971.2[医药卫生—药品]