生物功能表面及其在组织工程中的应用  

The Biologic Functional Surfaces and Their Applications in Tissue Engineering

作　　者：姚芳莲[1] 陈满[1] 张宏[1] 张海王月 安晓燕[1] 姚康德[2] 

机构地区：[1]天津大学化工学院高分子科学与工程系,天津300072 [2]天津大学高分子材料研究所,天津300072

出　　处：《生物医学工程学杂志》2007年第5期1177-1179,1199,共4页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(30470482/C010515);天津市自然科学基金重点项目资助(043803211)

摘　　要：材料生物功能表面的构筑,从材料学角度讲是通过材料表面工程使生物材料适应并被组织"接纳",赋予其动态整合性;从临床应用的角度,功能化表面接合周围组织与植入材料,起到"人工细胞外基质"的作用。生物功能表面的构筑在组织工程学中占有非常重要的地位。本文在简单介绍生物表面科学的基础上,综述了生物功能表面的构筑及其在组织工程中的应用。The construction of biologic functional surfaces of materials, from the visual angle of material science, is aimed to make the biomaterials adapted by tissues, and to endow them with dynamic conformity; moreover, from the view-point of clinical applications, it is the functional surface to join the environmental tissues with the implanted material, playing the role of artificial extracellular matrix（ECM）. The architecture of biologic functional surface is very important in tissue engineering science. Here the primary concepts of biological surface science and the construction and application of biofunctional surfaces in tissue engineering are reviewed.

关 键 词：生物表面科学 细胞外基质 细胞黏附 组织工程 

分 类 号：R318[医药卫生—生物医学工程]