灰色数列预测模型在骨髓基质细胞体外培养中的应用  

Prediction of the Marrow Stromal Cells with Grey Model

作　　者：何康[1] 冯有辉[1] 

机构地区：[1]广东医学院生理科学实验室,湛江524023

出　　处：《数理医药学杂志》2007年第5期717-719,共3页Journal of Mathematical Medicine

摘　　要：目的:探讨体外培养骨髓基质细胞(MSCs)传代时及其成骨诱导后碱性磷酸酶(ALP)活性的变化规律。方法:运用灰色GM(1,1)模型,对体外培养MSCs传代时及其成骨诱导后ALP活性进行分析和预测。结果:灰色GM(1,1)模型对体外培养MSCs传代时及其成骨诱导后ALP的活性变化的预测精度高,结果可靠。结论:体外培养的MSCs传代时及其成骨诱导后ALP的活性值的变化可用灰色GM(1,1)模型进行预测。Objective： To study the law of the osteogenesis of marrow stromal cell Methods： Grey mold GM（1, 1） was used to analyse and forecast the alkaline phosphatase（ALP） activity. The marrow stromal cells differentiations were evaluated by detecting activities of ALP using PNPP method after cultured for ld, 3d, 5d, and 7d respectively. Results： The forecast precision of grey mold GM（1,1） was high for the change of the ALP activity and the results were reliable. Conclusion： Grey model GM（1,1） could be used to predict differentiation of ostcogenesis of marrow stromal cells.

关 键 词：灰色模型 骨髓基质细胞 碱性磷酸酶 

分 类 号：R965[医药卫生—药理学]